Why would Asus put the 3rd PCI-e x16 (black on right?) right next to the 2nd PCI-e x16? If you got a dual slot cooler on your graphics cards, which a lot do, then it is totally useless. Can't go 3-way Crossfire if one wanted to.
Also, from what I can tell from looks alone, it doesn't look like their own Asus Xonar D2X will be able to fit into the top PCI-e x1 slot since it will hit the RAM. Kind of disappointing how their products aren't "perfectly" compatible with each other. A crossfire setup with double slot coolers alone will mean one can't use the Xonar D2X.