I just registered so that I could give my input on memory problems and the X38/X48 DDR3 motherboards I've had trouble with over the last month.
I purchased an Intel DX38BT motherboard and 8 GB of Patriot DDR3-1333 memory from newegg. I ran into troubles right away. I couldn't get it to boot reliably and when it did boot, it would crash several times an hour. I thought my problem was the power supply so I ordered a new PC Power And Coolling unit. When that didn't fix my problem I did a bunch of trouble shooting. I discovered that if I put in only 4 GB of ram, it would work fine. Thinking I had a bad set of memory, I returned one set and ordered a new one. When that had the same problem I tried putting in just the new set. Guess what, it worked! I discovered that I could put in either 4 GB set and it would work fine but filling all the slots with my full 8 GB didn't work at all.
Thinking that I had a bad Motherboard, I ordered a newer and more expensive Intel DX48BT2. I put it in, loaded all 8 GB of memory and had the same exact problem. It would run perfectly only if I only had two of the memory slots filled.
I posted a question on the MaximumPC forum and gforaker there was nice enough to point me to this post; http://www.tomshardware.com/reviews/x48-motherboard-comparison,1781-27.html
It looks to me like Intel's new chipset has a problem when you try to fill all the memory slots. In Tom's Hardware review, all four of their reviewed boards failed if they filled all the slots. This matches my experiance with the two Intel boards exactly.
I ordered Tom's Hardware's reference board the P5E3 Deluxe since they said that it would work. It did but it's not reliable. It was crashing several times a day with all the slots full. I tried tweeking the memory settings but it didn't change. Then I pulled out two of the memory modules and it hasn't crashed since.
I don't know if my problem is related to yours. I think that Intel has put out a chipset that has memory addressing problems. The only reason they're getting away with it is because DDR3 memory is expensive and most people are still running 32bit Windows so they're not filling up the slots. Down the road when memory becomes more expensive and more people are running Vista64 and they try to upgrade their memory, they're going to be in for a rude shock.
I think they should be sued. I've wasted several days of time trying to figure out why my new Windows 2008 64 bit development machine wouldn't work. I've contacted Intel and they say there's no problem. They didn't have a solution but they claim that their MB can accept 8 GB of memory but I still haven't found anyone who has it working.
Beware of the new Intel chipsets and DDR3. If I had it to do over, I'd probably stick with a DDR2 motherboard and memory.