Heck, I've been using a Harmony remote to control my lights for years.
Well, now apparently there's a hub extender to allow you to control more. I've never really worked with them too much, save for playing with them on the trade show floor or whatever. May have to check them out more.
ive used harmony's for years too epic customer service for those that cant even setup a self setting up TV! but seriously there customer support is the best around! oh and did I mention those remotes are very good too :)